TF-NRD v1.0 Dataset

Table S1.A: A non-redundant structure dataset of transcription factor-nucleic acid complexes.

PDB ID	Protein	Source Organism	Protein Length	Chain ID	Biological Assembly	Experimental Method	Protein Entities	RNA Entities	DNA Entities	Resolution (Å)	Oligomeric State	BSA
												Complex	Protein	Nucleic Acid
I. DNA-binding Transcription Factors
1A02	AP-1 FRAGMENT FOS + NUCLEAR FACTOR OF ACTIVATED T CELLS	H. sapiens	301+56	NFJ:AB	FJN:AB	X	3		2	2.7	Homodimer + Monomer	4166	2154	2012
1A0A	PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4	S. cerevisiae	63	AB:CD	AB:CD	X	1		2	2.8	Homodimer	2740	1429	1310
1AM9	STEROL REGULATORY ELEMENT BINDING PROTEIN 1A	H. sapiens	82	ABCD:EFGH	ABCD:EFGH	X	1		2	2.3	Homodimer	5382	2786	2596
1AN2	TRANSCRIPTION FACTOR MAX (TF MAX)	H. sapiens	86	A:B	AA′:BB′	X	1		1	2.9	Homodimer	2566	1286	1280
1AN4	UPSTREAM STIMULATORY FACTOR	H. sapiens	65	AB:CD	AB:CD	X	1		2	2.9	Homodimer	2839	1438	1401
1APL	MAT-ALPHA2 HOMEODOMAIN	S. cerevisiae	83	CD:AB	CD:AB	X	1		2	2.7	monomer	3519	1856	1662
1AWC	GA BINDING PROTEIN ALPHA + GA BINDING PROTEIN BETA 1	M. musculus	110+153	AB:DE	AB:DE	X	2		2	2.15	Heterodimer	1526	728	798
1B01	TRANSCRIPTIONAL REPRESSOR COPG	S. agalactiae	45	AB:EF	ABCD:EFGH	X	1		2	2.56	Homodimer	1429	717	712
1B3T	NUCLEAR PROTEIN EBNA1	E. virus	147	AB:CD	AB:CD	X	1		1	2.2	Homodimer	5243	2616	2627
1B72	HOMEOBOX PROTEIN HOX-B1 + PBX1	H. sapiens	87+97	AB:DE	AB:DE	X	2		2	2.35	Heterodimer	3304	1699	1606
1BC8	SAP-1 ETS DOMAIN	H. sapiens	93	C:AB	C:AB	X	1		2	1.93	Monomer	1710	816	894
1BF5	SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA	H. sapiens	575	A:BC	AA′:CD	X	1		2	2.9	Homodimer	3011	1511	1500
1BL0	MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN	E. coli	129	A:BC	A:BC	X	1		2	2.3	Monomer	2407	1201	1206
1BVO	TRANSCRIPTION FACTOR GAMBIF1	A. gambiae	175	A:DE	AA′:D′E	X	1		2	2.7	Monomer	770	427	343
1CF7	TRANSCRIPTION FACTOR DP-2 + TRANSCRIPTION FACTOR E2F-4	H. sapiens	76+95	AB:CD	AB:CD	X	2		2	2.6	Heterodimer	2654	1367	1287
1CGP	CATABOLITE GENE ACTIVATOR PROTEIN (CAP)	E. coli	205	AB:CDEF	AB:CDEF	X	1		2	3	Homodimer	2964	1512	1452
1CKT	HIGH MOBILITY GROUP 1 PROTEIN	R. norvegicus	71	A:BC	A:BC	X	1		2	2.5	Monomer	1630	839	791
1CMA	PROTEIN (MET REPRESSOR)	E. coli	104	AB:CD	ABEF:CDGH	X	1		2	2.8	Homodimer	1738	839	899
1D66	GAL4	S. cerevisiae	66	AB:DE	AB:DE	X	1		2	2.7	Homo 2-mer	2445	1191	1254
1DDN	DIPHTHERIA TOX REPRESSOR	C. diphtheriae	226	ABCD:EF	ABCD:EF	X	1		2	3	Homo 4-mer	5678	2801	2877
1DH3	TRANSCRIPTION FACTOR CREB	M. musculus	55	AC:BD	AC:BD	X	1		1	3	Homodimer	2350	1204	1145
1DP7	MHC CLASS II TRANSCRIPTION FACTOR HRFX1	H. sapiens	76	P:D	BP:AD	X	1		1	1.5	Homo 2-mer	3502	1845	1657
1EFA	LAC REPRESSOR	E. coli	333	ABC:DE	AB:DE	X	1		1	2.6	Homodimer	3517	1740	1777
1EGW	MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A	H. sapiens	77	ABCD:EFGH	AB:EF	X	1		2	1.5	Homodimer	2910	1568	1343
1EXJ	MULTIDRUG-EFFLUX TRANSPORTER REGULATOR	B. subtilis	278	A:M	AA′:MM′	X	1		1	3	Homodimer	2263	1067	1196
1GD2	TRANSCRIPTION FACTOR PAP1	S. pombe	70	EFGHIJ:ABCD	EF:AB	X	1		1	2	Homodimer	2660	1401	1259
1GLU	GLUCOCORTICOID RECEPTOR	R. norvegicus	81	AB:CD	AB:CD	X	1		1	2.9	Homodimer	2634	1256	1378
1GT0	OCTAMER-BINDING TRANSCRIPTION FACTOR 1 + TRANSCRIPTION FACTOR SOX-2	M. musculus	159+80	CD:AB	CD:AB	X	2		2	2.6	Hetero 2-mer	5483	2839	2644
1GXP	PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN	E. coli	106	ABEF:CDGH	AB:CD	X	1		2	2.5	Homodimer	3435	1715	1720
1H88	CCAAT/ENHANCER BINDING PROTEIN BETA + MYB PROTO-ONCOGENE PROTEIN	M. musculus	159+78	ABC:DE	ABC:DE	X	2		2	2.8	Homodimer + Monomer	4495	2343	2153
1HDD	ENGRAILED HOMEODOMAIN	D. melanogaster	61	CD:AB	CD:AB	X	1		2	2.8	Homo 2-mer	2699	1357	1342
1HJB	CCAAT/ENHANCER BINDING PROTEIN BETA + RUNT-RELATED TRANSCRIPTION FACTOR 1	M. musculus	123+87	ABCDEF:GHIJ	ABC:GH	X	2		2	3	Homodimer + Monomer	3785	1974	1811
1HWT	HEME ACTIVATOR PROTEIN	S. cerevisiae	81	CDGH:ABEF	CD:AB	X	1		2	2.5	Homodimer	2584	1349	1235
1IC8	HEPATOCYTE NUCLEAR FACTOR 1-ALPHA	H. sapiens	194	AB:EF	AB:EF	X	1		2	2.6	Homodimer	4929	2494	2434
1IF1	INTERFERON REGULATORY FACTOR 1	M. musculus	113	AB:CD	AB:CD	X	1		1	3	Homo 2-mer	4170	1987	2183
1IGN	RAP1	S. cerevisiae	246	AB:CDEF	A:CD	X	1		2	2.25	Monomer	4227	2098	2129
1IHF	INTEGRATION HOST FACTOR (ALPHA) (IHF) + INTEGRATION HOST FACTOR (BETA) (IHF)	E. coli	94+99	AB:CDE	AB:CDE	X	2		3	2.5	Hetero 2-mer	4755	2386	2369
1IO4	CAAT/ENHANCER BINDING PROTEIN BETA + CORE-BINDING FACTOR, BETA SUBUNIT + RUNT-RELATED TRANSCRIPTION FACTOR 1	M. musculus	123+141+78	ABCD:EF	ABCD:EF	X	3		2	3	Hetero 4-mer	3842	2046	1797
1JE8	Nitrate/Nitrite Response Regulator Protein NARL	E. coli	82	ABEF:CDGH	AB:CD	X	1		1	2.12	Homodimer	2946	1398	1547
1JFI	TATA-BOX-BINDING PROTEIN (TBP) + Transcription Regulator NC2 alpha chain + Transcription Regulator NC2 beta chain	H. sapiens	179+185+98	ABC:DE	ABC:DE	X	3		2	2.62	Hetero 3-mer	4253	2117	2136
1JMC	REPLICATION PROTEIN A (RPA)	H. sapiens	246	A:B	A:B	X	1		1	2.4	Monomer	2184	1023	1161
1JT0	HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION	S. aureus	194	ABCD:EF	ABCD:EF	X	1		1	2.9	Homo 4-mer	4888	2404	2484
1KU7	sigma factor sigA	T. aquaticus	73	AD:BC	AD:BC	X	1		2	2.4	Homodimer	1196	621	575
1L3L	Transcriptional activator protein traR	A. tumefaciens	234	ABCD:EFGH	BD:EG	X	1		1	1.66	Homodimer	2404	1182	1222
1LMB	LAMBDA REPRESSOR	E. phage lambda	92	12:34	34:12	X	1		2	1.8	Hetero 2-mer	2904	1450	1454
1LQ1	Stage 0 sporulation protein A	B. subtilis	120	CD:EF	CD:EF	X	1		2	2.3	Homo 2-mer	2382	1171	1212
1MDY	MYOD BHLH DOMAIN + MYOD BHLH DOMAIN	M. musculus	62+68	ABCD:EFGH	AB:EF	X	2		1	2.8	Homo 2-mer	2666	1389	1277
1MHD	SMAD3	H. sapiens	132	AB:CD	AB:CD	X	1		2	2.8	Homo 2-mer	1857	962	895
1MNM	MAT ALPHA-2 TRANSCRIPTIONAL REPRESSOR + MCM1 TRANSCRIPTIONAL REGULATOR	S. cerevisiae	100+87	ABCD:EF	ABCD:EF	X	2		2	2.25	Hetero 4-mer	6465	3231	3234
1MNN	NDT80	S. cerevisiae	340	A:BC	A:BC	X	1		2	1.4	Monomer	2661	1369	1292
1N6J	Calcineurin-binding protein Cabin 1 + Myocyte-specific enhancer factor 2B	H. sapiens	35+93	ABG:CD	ABG:CD	X	2		2	2.2	Hetero 3-mer	2721	1410	1311
1NGM	Transcription factor IIIB BRF1 subunit + Transcription initiation factor TFIID	S. cerevisiae	180+72	ABEFIJMN:CDGHKLOP	AB:CD	X	2		2	2.95	Hetero 2-mer	3121	1535	1586
1NKP	Max protein + Myc proto-oncogene protein	H. sapiens	83+88	ABDE:FGHJ	AB:FG	X	2		1	1.8	Hetero 2-mer	2794	1434	1360
1NLW	MAD + MAX PROTEIN	H. sapiens	76+80	ABDE:FGHJ	AB:FG	X	2		1	2	Hetero 2-mer	2679	1377	1302
1NVP	TATA box binding protein + Transcription initiation factor IIA alpha chain + Transcription initiation factor IIA beta chain + Transcription initiation factor IIA gamma chain	H. sapiens	108+181+ 57+76	ABCD:EF	ABCD:EF	X	4		2	2.1	Hetero 4-mer	3323	1654	1668
1OCT	OCT-1 POU DOMAIN	H. sapiens	156	C:AB	C:AB	X	1		2	3	Monomer	3157	1597	1560
1ODH	MGCM1	M. musculus	174	A:CD	A:CD	X	1		2	2.85	Monomer	1808	921	886
1P51	DNA-binding protein HU	N. sp.	94	ABCD:EFIH	AB:EF	X	1		1	2.5	Homodimer	3176	1629	1547
1PAR	ARC REPRESSOR	S. phage P22	53	ABCD:EF	ABCD:EF	X	1		2	2.6	Homo 4-mer	4140	2005	2134
1PDN	PRD PAIRED	D. melanogaster	128	C:AB	C:AB	X	1		2	2.5	Monomer	2562	1299	1263
1PNR	PURINE REPRESSOR	E. coli	340	A:B	AA′:BB′	X	1		1	2.7	Homodimer	3596	1813	1782
1PP7	39 kDa initiator binding protein	T. vaginalis	131	U:EF	U:EF	X	1		2	2.45	Monomer	1989	1017	971
1PUE	TRANSCRIPTION FACTOR PU.1	M. musculus	89	EF:ABCD	E:AB	X	1		2	2.1	Monomer	2018	962	1056
1QPI	TETRACYCLINE REPRESSOR	E. coli	203	A:MN	AA':MM′	X	1		2	2.5	Homodimer	2270	1152	1118
1QRV	HIGH MOBILITY GROUP PROTEIN D	D. melanogaster	73	AB:CD	AB:CD	X	1		1	2.2	Homo 2-mer	2505	1301	1204
1R71	Transcriptional repressor protein korB	E. coli	178	ABCD:EIFJGLHK	AB:EFIJ	X	1		2	2.2	Homo 2-mer	3734	1872	1862
1R8D	transcription activator MtaN	B. subtilis	109	AB:CD	AB:CD	X	1		2	2.7	Homodimer	3175	1535	1639
1RAM	TRANSCRIPTION FACTOR NF-KB P65	M. musculus	273	AB:CD	AB:CD	X	1		1	2.7	Homo 2-mer	2982	1458	1524
1RZR	Glucose-resistance amylase regulator + Phosphocarrier protein HPr	P. megaterium	332+88	GCADTLYS:HREB	CGLT:HR	X	3		2	2.8	Hetero 4-mer	3399	1679	1721
1SAX	Methicillin resistance regulatory protein mecI	S. aureus	123	AB:CD	AB:CD	X	1		2	2.8	homodimer	3065	1541	1524
1SKN	DNA-BINDING DOMAIN OF SKN-1	C. elegans	92	P:AB	P:AB	X	1		2	2.5	Monomer	1691	866	825
1SVC	NUCLEAR FACTOR KAPPA-B (NF-KB)	H. sapiens	365	P:D	PP′:DD′	X	1		1	2.6	Homodimer	4062	2065	1997
1T2K	Cyclic-AMP-dependent transcription factor ATF-2 + Interferon regulatory factor 3 + Transcription factor AP-1	H. sapiens	112+61+62	ABCD:EF	ABCD:EF	X	3		2	3	Hetero 4-mer	6018	2966	3052
1TQE	Histone deacetylase 9 + Myocyte-specific enhancer factor 2B	M. musculus	26+93	PQXRSY:CDEF	PQX:CD	X	2		2	2.7	Hetero 3-mer	3137	1630	1507
1TRR	TRP REPRESSOR	E. coli	107	ABDEGHJK:CFIL	ABGH:CI	X	1		1	2.4	Homo 4-mer	5536	2664	2872
1TTU	lin-12 And Glp-1 transcriptional regulator	C. elegans	477	A:BC	A:BC	X	1		2	2.85	Monomer	2138	1082	1055
1TUP	P53 TUMOR SUPPRESSOR	H. sapiens	219	ABC:EF	ABC:EF	X	1		2	2.2	Homo 3-mer	2057	1054	1004
1U8B	Ada polyprotein	E. coli	133	A:BCDE	A:BCDE	X	1		4	2.1	Monomer	2173	1030	1143
1UUT	REP PROTEIN	A. virus 5	197	AB:CD	A:C	X	1		1	2	Monomer	728	303	425
1VOL	TATA BINDING PROTEIN (TBP) + TRANSCRIPTION FACTOR IIB (TFIIB)	A. thaliana	200+204	AB:CD	AB:CD	X	2		2	2.7	Hetero 2-mer	3911	1895	2016
1VTN	HNF-3/FORK HEAD DNA-RECOGNITION MOTIF	H. sapiens	102	C:AB	C:AB	X	1		2	2.5	Monomer	2088	1055	1033
1W0T	TELOMERIC REPEAT BINDING FACTOR 1	H. sapiens	53	AB:CD	AB:CD	X	1		2	2	Homo 2-mer	3121	1576	1545
1XBR	T PROTEIN	X. laevis	184	AB:CD	AB:CD	X	1		1	2.5	Homodimer	4169	2112	2057
1XPX	Protein prospero	D. melanogaster	163	A:DC	A:CD	X	1		2	2.8	Monomer	847	446	401
1YRN	MAT A1 HOMEODOMAIN + MAT ALPHA2 HOMEODOMAIN	S. cerevisiae	61+83	AB:CD	AB:CD	X	2		2	2.5	Hetero 2-mer	3360	1778	1582
1YSA	GCN4	S. cerevisiae	58	CD:AB	CD:AB	X	1		2	2.9	Homo 2-mer	2258	1172	1086
1YTB	TATA BINDING PROTEIN (TBP)	S. cerevisiae	180	AB:CD	A:C	X	1		1	1.8	Monomer	2985	1486	1499
1YTF	TATA BINDING PROTEIN (TBP) + TRANSCRIPTION FACTOR IIA - TOA1C SUBUNIT + TRANSCRIPTION FACTOR IIA - TOA1N SUBUNIT + TRANSCRIPTION FACTOR IIA - TOA2 SUBUNIT	S. cerevisiae	121+180+ 53+79	ABCD:EF	ABCD:EF	X	4		2	2.5	Hetero 4-mer	3294	1645	1649
1Z9C	ZIF268	B. subtilis	87	ABCDEF:GHIJKL	AB:GH	X	1		2	2.64	Homo 2-mer	4126	2019	2107
1ZAA	PROLINE UTILIZATION TRANSCRIPTION ACTIVATOR	M. musculus	70	C:AB	C:AB	X	1		2	2.1	Monomer	2599	1393	1206
1ZME	PROLINE UTILIZATION TRANSCRIPTION ACTIVATOR	S. cerevisiae	70	CD:AB	CD:AB	X	1		2	2.5	Homodimer	2636	1310	1326
2A07	Forkhead box protein P2	H. sapiens	93	FGHIJK:ABCD	FGHIJK:ABCD	X	1		2	1.9	Homo 6-mer	5717	2772	2945
2BNW	ORF OMEGA	S. pyogenes	53	ABCD:EFGH	ABCD:EFGH	X	1		2	2.45	Homodimer	2926	1433	1493
2BOP	PROTEIN (E2)	B. papillomavirus	85	A:B	AA′:BB′	X	1			1.7	Homodimer	692	355	336
2BSQ	TRAFFICKING PROTEIN A + TRAFFICKING PROTEIN B	N. gonorrhoeae	146+77	ABCDEFGH:IJ	ABCDEFGH:IJ	X	2		2	3	Hetero 8-mer	3305	1646	1658
2C62	ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15	H. sapiens	66	AB:C	AB:C	X	1		1	1.74	Homo 2-mer	3029	1458	1571
2C9L	BZLF1 TRANS-ACTIVATOR PROTEIN	E. virus	63	YZ:AB	YZ:AB	X	1		2	2.25	Homo 2-mer	2337	1181	1156
2D5V	Hepatocyte nuclear factor 6	R. norvegicus	164	AB:CDEF	A:CD	X	1		2	2	Monomer	2741	1380	1361
2E1C	Putative HTH-type transcriptional regulator PH1519	P. horikoshii	171	A:BD	AC:BD	X	1		2	2.1	Homodimer	1030	523	507
2ER8	Regulatory protein LEU3	S. cerevisiae	72	ABCD:EFGH	AB:EF	X	1		1	2.85	Homodimer	2794	1384	1410
2ES2	Cold shock protein cspB	B. subtilis	67	A:B	A:B	X	1		1	1.78	Monomer	903	432	471
2GLI	FIVE-FINGER GLI	H. sapiens	155	A:CD	A:CD	X	1		2	2.6	Monomer	3121	1585	1537
2H27	RNA polymerase Sigma E factor	E. coli	73	AD:BCEF	A:BC	X	1		2	2.3	Monomer	1395	721	674
2NLL	RETINOIC ACID RECEPTOR + THYROID HORMONE RECEPTOR	H. sapiens	103+66	AB:CD	AB:CD	X	2		2	1.9	Hetero 2-mer	3206	1574	1632
2O49	DNA-binding protein SATB1	H. sapiens	93	A:BC	A:BC	X	1		2	2	Monomer	1108	557	552
2OR1	434 REPRESSORS	E. phage 434	69	LR:AB	LR:AB	X	1		2	2.5	Homo 2-mer	2772	1367	1405
2P5L	Arginine repressor	B. subtilis	64	CDGH:ABEF	CD:AB	X	1		2	2.85	Homodimer	2614	1296	1318
2QL2	Neurogenic differentiation factor 1	M. musculus	60	ABCD:EFGH	AB:EF	X	2		2	2.5	Homo 2-mer	2165	1102	1063
2R1J	Repressor protein C2	S. phage P22	68	LR:BA	LR:AB	X	1		2	1.53	Homo 2-mer	2654	1254	1400
2RBF	Bifunctional protein putA	E. coli	54	AB:CD	AB:CD	X	1		2	2.25	Homodimer	1598	806	792
2UZK	FORKHEAD BOX PROTEIN O3A	H. sapiens	97	AC:BDEF	A:BE	X	1		2	2.7	Monomer	1961	980	981
2VY1	PROTEIN LEAFY	A. thaliana	194	A:W	AB:WC	X	1		1	2.1	Homodimer	3404	1684	1720
2W7N	TRFB TRANSCRIPTIONAL REPRESSOR PROTEIN	E. coli	101	AB:EFGH	AB:EFGH	X	1		2	1.85	Homodimer	2999	1549	1450
2YPA	LIM DOMAIN-BINDING PROTEIN 1 + RHOMBOTIN-2 + T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 + TRANSCRIPTION FACTOR E2-ALPHA	H. sapiens	145+51+ 82+91	ABCD:EF	ABCD:EF	X	4		2	2.8	Hetero 4-mer	2239	1136	1103
2YVH	Transcriptional regulator	C. glutamicum	177	ABCD:EFGH	ABCD:EFGH	X	1		2	2.5	Homodimer	4985	2536	2449
2ZHG	Redox-sensitive transcriptional activator soxR	E. coli	154	A:B	AC:BD	X	1		1	2.8	Homodimer	2268	1020	1248
3A5T	Transcription factor MafG	M. musculus	107	AB:CD	AB:CD	X	1			2.8	Homodimer	2596	1343	1253
3BRD	Lin-12 and glp-1 phenotype protein 1, isoform a + Protein lin-12	C. elegans	29+477	AD:BC	A:BC	X	2		2	2.21	Hetero 2-mer	2024	1040	984
3BS1	Accessory gene regulator protein A	S. aureus	103	A:BC	A:BC	X	1			1.6	Monomer	1547	779	768
3CLC	Regulatory protein	E. sp. RFL1396	82	ABCD:EF	ABCD:EF	X	1		2	2.8	Homodimer	5270	2638	2632
3D2W	TAR DNA-binding protein 43	M. musculus	89	A:B	AA′:BB′	X	1		1	1.65	Homodimer	2643	1291	1352
3DFX	Trans-acting T-cell-specific transcription factor GATA-3	M. musculus	63	AB:XY	AB:XY	X	1		2	2.7	Homo 4-mer	3545	1792	1753
3DNV	HTH-type transcriptional regulator hipB + Protein hipA	E. coli	440+88	AB:T	AA′BB′:TT′	X	2			2.68	Homodimer	2825	1397	1428
3E6C	Cyclic nucleotide-binding protein	D. hafniense	250	C:BA	CF:ABDE	X	1		2	1.8	Homodimer	1353	653	700
3EYI	Z-DNA-binding protein 1	H. sapiens	72	AB:CD	AB:CD	X	1		1	1.45	Homo 2-mer	1463	720	743
3FDQ	Motility gene repressor mogR	L. monocytogenes serovar 1/2a	170	AB:CD	AB:CD	X	1		2	1.75	Homodimer	4165	2211	1954
3GFI	146aa long hypothetical transcriptional regulator	S. tokodaii	146	AC:DE	AC:DE	X	1		2	2.1	Homodimer	742	379	364
3GNA	V(D)J recombination-activating protein 1	M. musculus	96	A:DE	AA′:DD′EE′	X	1		2	2.4	Homodimer	1602	838	764
3GXQ	Putative regulator of transfer genes ArtA	S. aureus	54	AB:CD	AB:CD	X	1			2.35	Homodimer	1614	763	851
3GZ6	MutT/nudix family protein	S. oneidensis	240	AB:DC	AB:CD	X	1			2.9	Homodimer	4338	2307	2031
3H0D	CtsR	G. stearothermophilus	155	AB:DC	AB:CD	X	1			2.4	Homodimer	3811	1925	1886
3HTS	HEAT SHOCK TRANSCRIPTION FACTOR	K. lactis	102	B:A	BB′:AA′	X	1		1	1.75	Homodimer	2362	1165	1197
3IGM	PF14_0633 protein	P. falciparum	77	BA:WXCD	AB:CDWX	X	1		1	2.2	Homodimer	2971	1474	1498
3IKT	Redox-sensing transcriptional repressor rex	T. thermophilus	207	AB:CD	AB:CD	X	1		1	2.26	Homodimer	3339	1684	1655
3IV5	DNA-binding protein fis	E. coli	98	AB:CD	AB:CD	X	1		2	2.9	Homodimer	1957	1023	934
3JSO	LexA repressor	E. coli	202	AB:CD	AB:CD	X	1		1	2.29	Homodimer	3513	1618	1894
3KET	Redox-sensing transcriptional repressor rex	S. agalactiae serotype III	212	A:BC	AA′:BB′	X	1		2	2.4	Homodimer	1877	955	922
3LSP	DesT	P. aeruginosa	220	A:BD	AA′:BB′	X	1		2	2.66	Homodimer	3041	1554	1487
3MLN	Transcription factor COE1	M. musculus	224	ABE:CD	AB:CD	X	1		1	2.4	Homodimer	5095	2632	2463
3MZH	PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY)	M. tuberculosis	225	AB:CD	AB:CD	X	1		2	2.9	Homo 2-mer	2389	1191	1198
3N4M	Catabolite gene activator + DNA-directed RNA polymerase subunit alpha	E. coli	209+84	ABC:DE	ABCFGH:DEIJ	X	2		2	2.99	Hetero 6-mer	2910	1389	1520
3N7Q	Transcription termination factor, mitochondrial	H. sapiens	310	A:BC	A:BC	X	1		2	2.4	Monomer	1261	639	622
3O9X	Uncharacterized HTH-type transcriptional regulator ygiT	E. coli	133	AB:FE	AB:EF	X	1		2	2.1	Homo 2-mer	3059	1488	1571
3ON0	Protein traM	E. coli	127	ABCD:P	AA′BB′CC′DD′:PP′	X	1		1	2.87	Homotetramer	4680	2370	2311
3Q5F	Transcriptional regulator slyA	S. typhimurium	147	AB:CD	AB:CD	X	1		2	2.96	Homodimer	4205	2110	2095
3QMB	CpG-binding protein	H. sapiens	79	A:BC	A:BC	X	1		1	2.06	Monomer	1244	656	587
3RN2	Interferon-inducible protein AIM2	H. sapiens	208	AB:KL	AB:KL	X	1		1	2.55	Homo 2-mer	2089	986	1103
3TQ6	Transcription factor A, mitochondrial	H. sapiens	214	AB:CDEF	A:CD	X	1		2	2.45	Monomer	5353	2723	2630
3U3W	C-terminus heptapeptide from PapR protein + Transcriptional activator PlcR protein	B. thuringiensis	293+7	ABPQ:YZ	AB:YZ	X	2		2	2.4	Homodimer	2576	1292	1283
3UGM	TAL effector AvrBs3/PthA	X. oryzae pv. oryzae	1047	A:BC	A:BC	X	1		2	3	Monomer	6201	2884	3317
3UGO	RNA polymerase sigma factor	T. aquaticus	245	A:B	A:B	X	1		1	2.1	Monomer	1882	882	999
3UK3	Zinc finger protein 217	H. sapiens	57	CD:AB	CD:AB	X	1		2	2.1	Homo 2-mer	3193	1667	1526
3VOK	Transcriptional regulator	L. lactis subsp. lactis	189	A:U	AA′:UU′	X	1		1	2	Homodimer	1993	1000	993
3VWB	Virulence regulon transcriptional activator virB	S. flexneri	143	A:CB	A:BC	X	1		2	2.42	Monomer	1432	731	701
3W6V	AdpA	S. griseus	147	A:BC	A:BC	X	1		2	2.95	Monomer	1545	752	793
3ZHM	CI	L. phage TP901-1	79	A:BC	A:BC	X	1		2	2.6	Monomer	1329	639	690
3ZKC	HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR	B. subtilis	111	AB:CD	AB:CD	X	1		2	3	Homodimer	2675	1336	1339
3ZPL	PUTATIVE MARR-FAMILY TRANSCRIPTIONAL REPRESSOR	S. coelicolor	177	ABEF:CDGH	AB:CD	X	1		1	2.8	Homodimer	3862	1894	1968
3ZQL	PUTATIVE REPRESSOR SIMREG2	S. antibioticus	267	ABCD:EFGH	CD:GH	X	1		2	2.99	Homodimer	2674	1349	1325
3ZVK	ANTITOXIN OF TOXIN-ANTITOXIN SYSTEM VAPB + TOXIN OF TOXIN-ANTITOXIN SYSTEM	R. felis	134+78	ABCDEFGH:XY	ABCDEFGH:XY	X	2		2	2.5	Hetero 8-mer	3736	1874	1862
4EGY	Arabinose metabolism transcriptional repressor	B. subtilis	88	AB:TU	AB:TU	X	1		2	2.3	Monomer	3650	1890	1760
4F6M	Transcriptional regulator Kaiso	H. sapiens	133	A:DE	A:DE	X	1			2.4	Monomer	2706	1390	1315
4G7H	DNA-directed RNA polymerase subunit alpha + DNA-directed RNA polymerase subunit beta + DNA-directed RNA polymerase subunit beta' + DNA-directed RNA polymerase subunit omega + RNA polymerase sigma factor	T. thermophilus	1119+1524+ 315+443+99	ABCDEFKLMN OP:GHQR	ABCDEF:GH	X	5		2	2.9	Hetero 6-mer	6507	3096	3410
4G92	HAPB protein + HapE + Transcription factor HapC (Eurofung)	E. nidulans	119+64+92	ABC:DE	ABC:DE	X	3		2	1.8	Hetero 3-mer	3647	1783	1864
4H10	Polymerase cofactor VP35	H. sapiens	146	AB:CD	AB:CD	X	2		2	2.4	Heterodimer	2406	1270	1137
4HF1	Aryl hydrocarbon receptor nuclear translocator-like protein 1 + Circadian locomoter output cycles protein kaput	E. coli	71+73	AB:CD	AB:CD	X	1		2	2.22	Homodimer	3790	1886	1904
4HLY	K9	H. herpesvirus 8 type P	132	AB:CD	AB:CD	X	1		1	1.48	Homo 2-mer	938	463	474
4HQE	Transcriptional regulator QsrR	S. aureus	115	AB:CD	AB:CD	X	1		2	2.3	Homodimer	2483	1215	1268
4HQU	Platelet-derived growth factor subunit B	H. sapiens	109	A:C	AB:CD	X	1		1	2.2	Homodimer	314	132	182
4I2O	FixK2 protein	B. japonicum	243	AB:WX	AB:WX	X	1		2	1.77	Homodimer	2546	1240	1307
4IHT	HTH-type transcriptional regulator BenM	A. baylyi	94	ABCD:EFGH	AB:EF	X	1			3	Homodimer	3408	1722	1686
4IQR	Hepatocyte nuclear factor 4-alpha + Nuclear receptor coactivator 2	H. sapiens	13+338	ABEFIJKL:CDGH	AB:CD	X	2		2	2.9	homodimer	3434	1653	1780
4IZZ	Transcription Factor HetR	F. thermalis PCC 7521	302	AB:CD	AB:CD	X	1		1	2.5	Homodimer	2957	1463	1494
4J19	Homeobox-containing protein 1	H. sapiens	113	AB:CD	AB:CD	X	1		2	2.9	monomer	3165	1661	1504
4J2X	Four and a half LIM domains protein 1 + Recombining binding protein suppressor of hairless	M. musculus	28+427	ABCD:EFGH	AB:GH	X	2		2	2.85	Monomer	2203	1117	1086
4JCX	Csp231I C protein	C. sp. RFL231	98	AB:CD	AB:CD	X	1		2	2.3	Homodimer	2735	1365	1370
4JL3	Transcriptional regulator, TetR family	M. smegmatis	196	ABCD:EF	ABCD:EF	X	1		2	2.5	Homodimer	5703	2900	2803
4KFC	KDP operon transcriptional regulatory protein KdpE	E. coli	227	AB:YZ	AB:YZ	X	1		2	2.53	Homodimer	2985	1422	1564
4L62	Transcriptional regulator	P. aeruginosa	190	ABCDEFGHIJKL MNOP:QRSTUVWX	ABCD:QR	X	1		2	2.9	Homodimer	4339	2204	2135
4LDX	Auxin response factor 1	A. thaliana	363	AB:CD	AB:CD	X	1		2	2.9	Homodimer	3550	1810	1740
4LLN	MepR	S. aureus	140	ABCDIJ:GHEFKL	AB:GH	X	1		1	2.84	Homodimer	4025	1951	2075
4LMG	Iron-regulated transcriptional activator AFT2	S. cerevisiae	157	ABCD:EFGH	AD:GH	X	1		2	2.2	Monomer	2919	1426	1493
4LUP	RNA polymerase sigma factor	E. coli	106	AC:BD	A:B	X	1		1	1.2	Monomer	1288	590	698
4M8B	YHR177W	S. cerevisiae	202	R:AB	R:AB	X	1		2	2.61	Monomer	2162	1094	1068
4MTD	Zinc uptake regulation protein	E. coli	171	ABCD:YZ	ABCD:YZ	X	1		2	2.5	Homodimer	5978	2968	3010
4NHJ	DNA-binding transcriptional regulator RstA	K. pneumoniae subsp. pneumoniae	119	AB:CD	AB:CD	X	1		2	2.7	Homodimer	3236	1670	1566
4ON0	NolR	R. fredii	118	ABCD:EGFH	AB:EF	X	1		2	3	Homodimer	2982	1489	1492
4PZI	Histone-lysine N-methyltransferase 2B	H. sapiens	67	A:BC	A:BC	X	1		1	2.15	Monomer	1705	877	827
4QTJ	White-opaque regulator 1	C. albicans	274	A:BC	A:BC	X	1		2	2.1	Monomer	1513	768	745
4R22	HTH-type transcriptional regulator TnrA	P. megaterium	82	B:G	BB′:GG′	X	1		1	2.6	Homodimer	3016	1440	1577
4RB1	DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport t (Fur family)	M. gryphiswaldense	145	AB:D	AA′BB′:DD′	X	1		1	2.75	Homodimer	5590	2829	2761
4ROC	TATA-box-binding protein + Transcription factor IIIB 50 kDa subunit	H. sapiens	183+360	AB:NT	AB:NT	X	2		2	1.9	Hetero dimer	4919	2401	2518
4UX5	TRANSCRIPTION FACTOR MBP1	P. oryzae	136	AB:CD	AB:CD	X	1		2	2.4	Monomer	2883	1448	1436
4WLS	HTH-type transcriptional regulator CueR	E. coli	128	AB:XYUV	AB:XY	X	1		4	2.11	Homodimer	2864	1400	1465
4WU4	Response regulator receiver domain protein	NA	68	AB:GH	AB:GH	X	1		2	2.3	Homodimer	2159	1048	1112
4XRM	Homeobox protein Meis2	H. sapiens	64	AB:ML	AB:LM	X	1		2	1.6	Monomer	2469	1269	1199
4Y00	TAR DNA-binding protein 43	H. sapiens	103	ABCD:EFGH	A:E	X	1		1	3	Monomer	1455	663	792
4Z3C	Methylcytosine dioxygenase	H. sapiens	52	C:AB	C:AB	X	1		1	1.57	Monomer	1349	702	647
5D23	Fibroin-modulator-binding protein-1	B. mori	102	A:B	A:B	X	1		1	1.95	Monomer	2412	1263	1149
5D8C	MerR family regulator protein	H. influenzae	137	AB:CD	AB:CD	X	1		2	2.25	Homodimer	2618	1257	1361
5DY0	TetR family transcriptional regulator	C. glutamicum	230	ABCD:EFGH	AB:EF	X	1		1	3	Homodimer	3308	1674	1634
5EG6	Recombining binding protein suppressor of hairless + hRITA	M. musculus	16+422	CR:BA	CR:AB	X	2		2	2.09	Hetero 2-mer	1421	709	712
5EYB	DNA-binding protein reb1	S. pombe	362	AB:CDEF	A:CD	X	1		2	2.7	Monomer	4476	2183	2294
5F7Q	Lmo0178 protein	L. monocytogenes serovar 1/2a	407	CEJL:FK	CEJL:FK	X	1		2	2.4	Homodimer	9054	4692	4361
5FD3	Protein lin-54 homolog	H. sapiens	135	AB:CDHI	A:HI	X	1		2	2.42	Monomer	1971	927	1043
5FMP	HTH-TYPE TRANSCRIPTIONAL REPRESSOR KSTR	M. tuberculosis	205	AB:CD	AB:CD	X	1		2	2.26	Homodimer	2283	1129	1155
5GNJ	Transcription factor MYC2	A. thaliana	89	GIABEFMN:KL CDHJOP	GI:KL	X	1		2	2.7	Homodimer	2156	1122	1034
5GPC	Transcriptional regulator (TetR/AcrR family)	H. halodurans	194	ABCD:GE	ABCD:GE	X	1		2	2.8	Homodimer	4359	2127	2232
5GZB	Transcriptional enhancer factor TEF-3	H. sapiens	107	A:BC	A:BC	X	1		2	2.7	Monomer	2061	1057	1005
5H3R	Multiple antibiotic resistance protein MarR	E. coli	147	AB:CD	AB:CD	X	1		2	2.67	Homodimer	3489	1741	1748
5HLG	MarR family transcriptional regulator	S. epidermidis	148	ABCDEFGH:IJKL MNOP	AB:IJ	X	1		1	3	Homodimer	3944	1944	2000
5HSO	Uncharacterized HTH-type transcriptional regulator Rv2887	M. tuberculosis	160	ABCD:EF	ABCD:EF	X	1		2	2.5	Homodimer	1736	882	854
5I44	Chromosome-anchoring protein RacA	B. subtilis	69	BADEGFHIJK:UTZRPW	ABDE:UW	X	1		1	2.62	Homodimer	4158	2082	2076
5J2Y	Regulatory protein	P. aeruginosa	80	AB:FR	A:F	X	1		2	2.4	Monomer	645	328	317
5J3E	Thymocyte nuclear protein 1	H. sapiens	225	AB:CDEF	A:EF	X	1		1	2.6	Monomer	1069	519	551
5JGH	ARS-binding factor 2, mitochondrial	S. cerevisiae	163	ADGJ:BCEFHIKL	AD:BCEF	X	1		2	2.6	monomer	8913	4548	4365
5JLT	Middle transcription regulatory protein motA	E. phage T4	125	ABCD:EFGH	A:EF	X	1		2	2.96	Monomer	2025	1030	995
5JUB	ComS + Transcriptional regulator	S. thermophilus	310+8	ABCD:XZ	AB:XZ	X	2		2	2.57	Homodimer	2275	1092	1182
5K5Q	AspA	S. sp. NOB8H2	92	CDABEF:PN	ABCDEF:NP	X	1		2	2.65	Homodimer	8897	4488	4410
5K7Z	Transcriptional regulator, TetR family	M. xanthus	231	ABCD:EF	AB:EF	X	1		1	2.92	Homo 2-mer	2313	1151	1161
5LEJ	Listeriolysin regulatory protein	L. monocytogenes serovar 1/2a	237	AB:CD	AB:CD	X	1		2	2.7	Homodimer	2735	1345	1390
5LXU	Transcription factor LUX	A. thaliana	57	A:UB	A:BU	X	1		2	2.14	Monomer	1363	682	681
5MHJ	Major viral transcription factor ICP4	H. herpesvirus 1	201	AB:EF	AB:EF	X	1		2	2.12	Homodimer	1630	862	768
5MPF	Grainyhead-like protein 1 homolog	H. sapiens	238	AB:EF	AB:EF	X	1		1	2.92	Homodimer	2595	1364	1231
5OND	Transcription antitermination protein RfaH	E. coli	162	AB:CD	A:C	X	1		1	2.1	Monomer	863	376	487
5TW1	DNA-directed RNA polymerase subunit alpha + DNA-directed RNA polymerase subunit beta + DNA-directed RNA polymerase subunit beta' + DNA-directed RNA polymerase subunit omega + RNA polymerase sigma factor SigA + RNA polymerase-binding protein RbpA + Unknown peptide	M. smegmatis	107+114+ 1169+ 1317+17+ 350+ 466	JABCDEFT:OP	ABCDEFJT:OP	X	7		2	2.76	Hetero 9-mer	4923	2400	2523
5VL9	Regulatory protein TetR	E. lignolyticus	192	ABCD:EFGH	AB:EFGH	X	1		2	2.16	homodimer	2471	1277	1194
5WX9	Ethylene-responsive transcription factor ERF096	A. thaliana	131	A:BC	A:BC	X	1		2	1.76	Monomer	2612	1357	1256
5X11	Transcriptional regulator	B. spizizenii	188	ABCDEFGH:IJMN	AB:IJ	X	1		2	2.65	Homodimer	4222	2121	2101
5X5L	AdeR	A. baumannii	109	ABEHMN:CDFG	ABEHMN:CDFG	X	1		2	2.75	Homodimer	7244	3563	3680
5XFP	PHD finger protein 1	H. sapiens	336	ABE:CD	B:CD	X	1		1	2.3	Monomer	1011	526	485
5XFQ	PHD finger protein 1 + Peptide from Histone H3	M. musculus	13+336	ABEF:CD	AB:CD	X	2		1	2.4	homo 2-mer	994	505	489
5XSK	Hepatoma-derived growth factor	R. norvegicus	120	AB:DF	AB:DF	X	1		2	2.84	Homodimer	720	335	385
5YEJ	TetR family transcriptional regulator	M. smegmatis	232	ABC:DFG	BC:DF	X	1		2	2.7	Homodimer	2863	1407	1456
5YI2	Zinc transport transcriptional regulator	L. lactis subsp. lactis	146	ABEFIJMN:CGK ODPLH	AB:CD	X	1		1	2.6	Homodimer	2596	1310	1286
5ZD4	Maltose-binding periplasmic protein, Protein BRASSINAZOLE-RESISTANT 1	A. thaliana	453	CDAB:GHEF	CD:GH	X	1		1	2.17	Homodimer	3065	1560	1505
5ZGN	KacA + KacT	K. pneumoniae subsp. pneumoniae	177+88	ABCDEF:GH	ABCDEF:GH	X	2		2	2.24	Hetero 6-mer	3687	1865	1822
6ASB	F-box/LRR-repeat protein 19	H. sapiens	123	CFIL:ABDEGHJK	A:BC	X	1		1	2.85	Monomer	1707	888	820
6C2S	Transcriptional regulator, MarR family	R. palustris	186	ABCD:UVXY	AD:UV	X	1		2	2.85	Homodimer	3000	1511	1490
6C31	TetR family transcriptional regulator	M. tuberculosis	214	ABCDEFGH:IJKL	ABCD:KL	X	1		2	3	Homodimer	5553	2752	2802
6CG8	UPF0335 protein B7Z12_12435	C. vibrioides	78	ABDE:CF	ABDE:CF	X	1		2	2.3	Homodimer	1395	684	711
6CHV	Antitoxin HigA	P. vulgaris	121	ACBDGH:IJEFKL	AC:IJ	X	1		2	2.9	Homodimer	2582	1288	1294
6CRO	LAMBDA CRO REPRESSOR	E. phage lambda	60	A:RU	AB:RUCD	X	1		2	3	Homodimer	1397	735	661
6EL8	Forkhead box protein N1	H. sapiens	99	AD:BCEF	A:BC	X	1		2	1.61	Monomer	1481	755	726
6FAS	B3 domain-containing transcription repressor VAL1	A. thaliana	119	AB:CDEF	A:CD	X	1		2	1.9	Monomer	1386	691	695
6FN0	Cryptochrome photoreceptor	C. reinhardtii	499	A:CD	A:CD	X	1		2	2.9	Monomer	1861	902	959
6G1T	AM32	E. faecalis	122	A:ED	A:DE	X	1		2	1.93	Monomer	3231	1599	1633
6HP7	SPBc2 prophage-derived uncharacterized protein YopK	B. subtilis	386	AB:CD	AB:CD	X	1		2	2.2	Homodimer	4010	1925	2085
6IDE	Transcriptional regulator LuxR family	V. cholerae	256	AB:CD	AB:CD	X	1		2	2.51	Homodimer	2586	1285	1301
6IR8	OsWRKY45	O. sativa subsp. japonica	69	A:BC	A:BC	X	1		2	2.3	Monomer	1218	615	603
6J4F	Probable WRKY transcription factor 2	A. thaliana	82	BF:CDGH	B:CD	X	1		2	2.4	Monomer	1259	619	641
6JBX	Fatty acid biosynthesis transcriptional regulator	S. pneumoniae	152	AB:CD	AB:CD	X	1		2	2.2	Homodimer	3613	1762	1851
6JGW	CadR	P. putida	147	BA:CD	AB:CD	X	1		2	2.8	Homodimer	3043	1431	1612
6LB3	HTH cro/C1-type domain-containing protein	P. aeruginosa	109	ABCDEFGH: IJKLMN	ABGH:IJ	X	1		2	2.5	Homo 4-mer	3367	1634	1733
6LUI	Atherin	H. sapiens	80	A:BC	A:BC	X	1		2	1.78	Monomer	1534	794	740
6LXN	Transcriptional regulatory protein OmpR	E. coli	113	AB:CD	AB:CD	X	1		2	2.93	Homodimer	3424	1712	1711
6MRJ	Nickel-responsive regulator	H. pylori	148	ABCD:LM	ABCD:LM	X	1		2	2.8	Homo 4-mer	3819	1901	1918
6NSM	TetR family transcriptional regulator CifR	P. aeruginosa	198	AB:CD	AB:CD	X	1		2	2.8	Homodimer	3617	1886	1730
6ON0	Gp39	R. N15	71	AB:CN	AB:CN	X	1		1	1.6	Homodimer	1977	997	980
6P0S	DNA-binding protein Fis + Excisionase	E. phage lambda	55+98	ABE:CD	ABE:CD	X	2		2	2.7	FiS homodimer and Excisionase monomer monomer	3543	1797	1745
6P1A	Q protein	E. phage 21	162	ABC:DEFG	AB:DE	X	1		2	2.84	Homo 2-mer	3400	1793	1607
6Q2B	MarR family transcriptional regulator	L. monocytogenes serovar 1/2a	153	AB:CD	AB:CD	X	1		1	2.72	Homodimer	4511	2277	2234
6QFD	DNA-binding protein	H. salinarum	116	ABCD:EFGH	AB:EF	X	1		2	2.13	Homodimer	3484	1715	1770
6RYD	Protein WUSCHEL	A. thaliana	76	ABEF:CDGH	EF:GH	X	1		2	1.58	Homodimer	3016	1576	1440
6W1A	Transcriptional regulator	S. dysgalactiae	284	AB:EF	AB:EF	X	1		2	2.8	Homodimer	2465	1203	1262
6ZA3	Transcriptional regulator, GntR family	A. fabrum	250	AB:EF	AB:EF	X	1		1	2.05	Homodimer	2214	1075	1139
7AMN	HTH-type transcriptional regulator LuxR	V. alginolyticus	221	BA:EF	AB:EF	X	1		2	2.3	Homodimer	3488	1752	1736
7B0C	HTH-type transcriptional repressor NsrR	S. coelicolor	161	AB:CD	AB:CD	X	1		2	3	Homodimer	3469	1743	1726
7BCB	KORA domain-containing protein	E. coli	110	AB:CD	AB:CD	X	1		2	2.8	Homodimer	2317	1173	1144
7BHY	Deoxyribonucleoside regulator	B. subtilis	57	ABC:EG	AB:EG	X	1		2	2.3	Homodimer	1829	945	884
7BZG	HTH-type transcriptional activator HxlR	B. subtilis	123	ABEFIJ: CDGHKL	AB:CD	X	1		1	2.9	Homodimer	2943	1400	1543
7C0G	Aca1	P. phage JBD30	79	AB:CD	AB:CD	X	1		1	2.4	Homo 2-mer	951	497	454
7C9O	Nuclear transcription factor Y subunit B-11 + Nuclear transcription factor Y subunit C-2 + Zinc finger protein HD1	O. sativa subsp. japonica	104+67+95	ABC:DE	ABC:DE	X	3		2	2.55	Trimer	3464	1680	1784
7DVV	HTH marR-type domain-containing protein	S. agalactiae serotype III	153	AB:LM	AB:LM	X	1		2	2.49	Homodimer	4640	2313	2326
7EL3	Homoprotocatechuate degradation operon regulator HpaR	A. baumannii	141	AB:CD	AB:CD	X	1		2	1.7	Homodimer	4273	2152	2121
7EOF	Coiled-coil domain-containing protein 25	H. sapiens	204	BA:CD	AB:CD	X	1		2	2.73	NA	376	196	180
7ET4	AP2/ERF and B3 domain-containing transcription repressor TEM1	A. thaliana	122	ADGJ: BCEFHIKL	A:BC	X	1		2	2.7	Monomer	1608	792	816
7ET6	AP2/ERF and B3 domain-containing transcription repressor TEM1	A. thaliana	125	DA:EF	AD:EF	X	1		2	2.7	monomer	2565	1224	1341
7F2F	Serine-rich protein TYE7	S. cerevisiae	136	AB:EH	AB:EH	X	1		2	2.55	Homodimer	2904	1444	1460
7F9H	EnrR repressor	E. piscicida	90	AB:CD	AB:CD	X	1		1	1.78	Monomer	3156	1515	1642
7JNP	HTH-type transcriptional regulator MtrR	N. gonorrhoeae	213	AB:CD	AB:CD	X	1		2	2.6	Homodimer	2366	1172	1194
7LH9	Bromodomain-containing protein 1	H. sapiens	126	ABCD: EFGHIJKL	A:EFE′F′	X	1		1	2.6	Monomer	1426	715	711
7OYK	Central glycolytic genes regulator	B. subtilis	96	ABCD:EFGH	AD:EF	X	1		2	2.1	Homodimer	1672	896	775
7PRV	Glucocorticoid receptor + Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	H. sapiens	21+393	ABF:CD	ABF:CD	X	2		2	2.7	homodimer	2622	1302	1320
7PZA	Putative cAMP-binding protein-catabolite gene activator	R. meliloti	244	AB:CDEF	AB:CDEF	X	1		2	2.72	Homodimer	2506	1259	1247
7T8K	BrxR	A. sp. NEB 394	291	AB:CD	AB:CD	X	1		2	2.3	Homodimer	3192	1610	1582
7TZ1	Immunity repressor	M. phage TipsytheTRex	203	A:BC	A:BC	X	1		2	2.79	Monomer	3120	1567	1554
7V6W	Antitoxin + Putative mRNA interferase YoeB	S. aureus	85+89	FBCAEM LIKNDJ: GHPO	ABCDEF:GH	X	2		2	2.55	homodimer	3635	1831	1804
7V9F	BEN domain-containing protein 3	M. musculus	114	A:BC	A:BC	X	1		2	2.5	Monomer	579	261	318
7VJQ	anti-CRISPR-associated protein Aca2	P. phage ZF40	121	AB:CD	AB:CD	X	1		2	2.79	Homodimer	2268	1175	1093
7VP1	Transcription factor TCP10	A. thaliana	107	AB:CD	AB:CD	X	1		2	2.9	Homo 2-mer	2408	1224	1184
7X5G	Nuclear factor erythroid 2-related factor 2 + Transcription factor MafG	H. sapiens	104+113	ABEF:CDGH	AB:CD	X	2		2	2.3	Heterodimer	2771	1423	1348
7XQ5	Protein INO2 + Protein INO4	S. cerevisiae	73+75	AB:CD	AB:CD	X	2		2	2.25	Heterodimer	3239	1649	1590
7YUK	Protein BANP	H. sapiens	141	A:CD	A:CD	X	1		1	2.11	Monomer	1338	658	680
7YZG	Forkhead box protein H1	X. laevis	140	A:BC	A:BC	X	1		2	2.82	Monomer	2363	1168	1195
7ZG5	Acetyltransferase + DUF1778 domain-containing protein	S. typhimurium	176+94	ABCD:EF	ABCD:EF	X	2		2	2	Homodimer	543	269	274
8B4B	Cholera toxin transcriptional activator	V. cholerae serotype O1	110	WXYZ:LM	WXYZ:LM	X	1		2	1.75	Monomer tandem repeat	4927	2400	2527
8EB5	Hermes transposase BED domain	M. domestica	78	A:CD	AA':CC'	X	1		2	2.5	Monomer repeat	3163	1569	1594
8EJO	Homeobox domain-containing protein	O. anatinus	71	AB:CD	AB:CD	X	1		2	2.67	Homodimer	3626	1826	1800
8HML	DNA-binding response OmpR family regulator	S. erythraea	143	AB:DC	AB:CD	X	1		2	2.95	Monomer tandem repeat	3232	1606	1626
8IKE	LMX1A factor	H. sapiens	60	C:AB	C:AB	X	1		2	2.6	Monomer	1537	750	787
8J0K	Transcription factor AP-2-alpha	H. sapiens	219	AB:CD	AB:CD	X	1		2	2.1	Homodimer	2263	1156	1107
8K4L	Nuclear respiratory factor 1	H. sapiens	109	A:C	AB:CD	X	1		1	2.3	Homodimer	3068	1506	1562
8K86	Nuclear factor interleukin-3-regulated protein	H. sapiens	73	AB:CD	AB:CD	X	1		2	2.06	Homodimer	2481	1283	1198
8P5Q	Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 3	A. thaliana	129	A:BC	A:BC	X	1		2	2.14	Monomer	2121	1054	1067
8PW0	Iron dependent repressor, putative	D. radiodurans	148	A:B	AA':BB'	X	1		1	2.2	Homodimer	3276	1652	1624
8UVK	DNA-binding response regulator	C. jejuni	224	AB:CD	AB:CD	X	1		2	2.21	Homodimer	2781	1392	1389
8YEY	Activating signal cointegrator 1	H. sapiens	148	CA:DB	AC:BD	X	1		1	2	monomer	1003	482	521
1A66	CORE NFATC1	H. sapiens	178	A:BC	A:BC	N	1		2		Monomer	2213	1085	1128
1AHD	Homeotic protein antennapedia	D. melanogaster	68	P:AB	P:AB	N	1		2		Monomer	2290	1159	1130
1C7U	MYOCYTE-SPECIFIC ENHANCER FACTOR 2A, C4 FORM	H. sapiens	85	AB:CD	AB:CD	N	1		1		Homodimer	3490	1807	1683
1CJG	PROTEIN (LAC REPRESSOR)	E. coli	62	AB:CD	AB:CD	N	1		1		Homodimer	3780	1832	1948
1CO0	TRP OPERON REPRESSOR	E. coli	107	AB:EF	AB:EF	N	1		2		Homodimer	3006	1516	1491
1F4S	ETHANOL REGULON TRANSCRIPTIONAL FACTOR	E. nidulans	65	P:AB	P:AB	N	1		2		Monomer	2211	1162	1049
1G4D	REPRESSOR PROTEIN C	E. phage Mu	69	A:BC	A:BC	N	1		2		Monomer	1708	888	819
1GAT	ERYTHROID TRANSCRIPTION FACTOR GATA-1	G. gallus	60	A:BC	A:BC	N	1		2		Monomer	2036	1039	997
1GCC	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1	A. thaliana	63	A:BC	A:BC	N	1		2		Monomer	1612	832	780
1HRY	HUMAN SRY	H. sapiens	76	A:BC	A:BC	N	1		2		Monomer	2106	1136	971
1J4W	FUSE binding protein	H. sapiens	174	A:B	A:B	N	1		1		Monomer	2045	994	1052
1KQQ	DEAD RINGER PROTEIN	D. melanogaster	139	A:BC	A:BC	N	1		2		Monomer	1745	863	882
1LFU	homeobox protein PBX1	M. musculus	82	P:AB	P:AB	N	1		2		Monomer	2210	1178	1032
1LO1	Steroid hormone receptor ERR2	H. sapiens	98	A:BC	A:BC	N	1		2		Monomer	2452	1245	1208
1MSE	C-Myb DNA-Binding Domain	M. musculus	105	C:AB	C:AB	N	1		2		Monomer	2841	1358	1483
1O4X	Transcription factor SOX-2+transcription factor Oct-1	H. sapiens	167+88	AB:CD	AB:CD	N	2		2		Heterodimer	4894	2516	2379
1TF3	TRANSCRIPTION FACTOR IIIA	X. laevis	92	A:EF	A:EF	N	1		2		Monomer	3255	1638	1616
1XS9	DNA-directed RNA polymerase alpha chain + Multiple antibiotic resistance protein marA	E. coli	132+84	AD:BC	A:BC	N	2		2		Monomer	2795	1407	1388
1YUI	GAGA-FACTOR	D. melanogaster	54	A:BC	A:BC	N	1		2		Monomer	2359	1243	1116
1ZGW	Ada polyprotein	E. coli	139	A:BC	A:BC	N	1		2		Monomer	2457	1242	1214
2HDC	TRANSCRIPTION FACTOR	R. norvegicus	97	A:BC	A:BC	N	1		2		Monomer	2375	1185	1190
2JX1	Myelin transcription factor 1	M. musculus	31	A:BC	A:BC	N	1		2		Monomer	1419	754	666
2K1N	AbrB family transcriptional regulator	B. subtilis	55	ABCD:EF	ABCD:EF	N	1		2		Homodimer	3049	1419	1630
2KAE	GATA-type transcription factor	C. elegans	71	A:BC	A:BC	N	1		1		Monomer	2962	1585	1376
2KKF	Histone-lysine N-methyltransferase HRX	H. sapiens	59	A:BC	A:BC	N	1		1		Monomer	1904	1009	894
2KMK	Zinc finger protein Gfi-1	R. norvegicus	82	A:BC	A:BC	N	1		2		Monomer	2762	1430	1331
2KO0	THAP domain-containing protein 1	H. sapiens	87	A:BC	A:BC	N	1		2		Monomer	2171	1141	1030
2LEF	LYMPHOID ENHANCER-BINDING FACTOR	M. musculus	86	A:BC	A:BC	N	1		2		Monomer	3677	1884	1793
2LEV	Ler	E. coli O157:H7	57	A:BC	A:BC	N	1		2		Monomer	928	454	474
2LEX	Probable WRKY transcription factor 4	A. thaliana	78	A:BC	A:BC	N	1		2		Monomer	1200	591	609
2MAP	RNA polymerase sigma factor	E. coli	96	A:B	A:B	N	1		1		Monomer	1433	665	768
2MRU	Antitoxin MazE	E. coli	67	AB:XY	AB:XY	N	1		2		Homodimer	1675	865	810
2MXF	MvaT	P. aeruginosa	55	A:BC	A:BC	N	1		1		Monomer	1637	851	785
2O8K	RNA polymerase sigma factor RpoN	A. aeolicus	63	A:BC	A:BC	N	1		2		Monomer	1553	745	808
2P7C	Penicillinase repressor	B. licheniformis	82	B:AC	B:AC	N	1		2		Monomer	2320	1099	1222
2STT	ETS1	H. sapiens	96	A:BC	A:BC	N	1		2		Monomer	1815	907	907
2Z33	Phosphate regulon transcriptional regulatory protein phoB	E. coli	104	A:BC	A:BC	N	1		2		Monomer	1968	979	989
II. RNA-binding Transcription Factors

1C9S	TRP RNA-BINDING ATTENUATION PROTEIN	G. stearothermophilus	74	ABCDEF GHIJK LMNOPQ RSTUV:W	ABCDEF GHIJK LMNOPQ RSTUV:W	X	1	1		1.9	Homo 11-mer	1050	502	548
1L1C	Transcription antiterminator licT	B. subtilis	55	AB:C	AB:C	N	1	1			Homodimer	2352	1168	1184
1QFQ	36-mer N-terminal peptide of the N protein	E. phage lambda	35	B:A	B:A	N	1	1			Monomer	1322	674	648
1WMQ	Hut operon positive regulatory protein	B. subtilis	147	AB:CD	AEI:CGK	X	1	1		1.6	Homodimer	4585	2038	2546
2A8V	RNA BINDING DOMAIN OF RHO TRANSCRIPTION TERMINATION FACTOR	E. coli	118	ABC:DE	A:D	X	1	2		2.4	Monomer	719	281	438
2ASB	Transcription elongation protein nusA	M. tuberculosis	251	A:B	A:B	X	1	1		1.5	Monomer	2316	1092	1225
3KS8	Polymerase cofactor VP35	R. ebolavirus	184	ABCD:EF	AB:EF	X	1	2		2.4	Homo 2-mer	1663	799	864
3R2C	30S ribosomal protein S10 + N utilization substance protein B	A. aeolicus	148+83	ABJK:RS	AJ:R	X	2	1		1.9	Heterodimer	2278	1027	1251
4GHA	Polymerase cofactor VP35	O. marburgense	146	ACEG:IJ	ACEG:IJ	X	1	1		2.5	monomer	3691	1774	1917
5M3H	Polymerase acidic protein + Polymerase basic protein 2 + RNA-directed RNA polymerase catalytic subunit + TYR-SER-PRO-THR-SEP-PRO	H. sapiens	28+728+776+ 797	ABCXY:RV	ABCXY:RV	X	4	2		2.5	Hetero 5-mer	5352	2563	2789
6FHI	Polymerase acidic protein + Polymerase basic protein 2 + RNA-directed RNA polymerase catalytic subunit + TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER-PRO- SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR	H. sapiens, Influenza A virus	19+738+776+8 09	ABCX:RV	ABCX:RV	X	4	2		2.8	Hetero 4-mer	5460	2627	2833
8F5G	Transcription termination/ antitermination protein NusG	T. pseudethanolicus	182	ABC:DEF	A:D	X	1	1		2.7	Monomer	1529	751	778
III. DNA/RNA-binding Transcription Factors

5XOG	DNA-directed RNA polymerase subunit + DNA-directed RNA polymerase subunit + DNA-directed RNA polymerase subunit beta + RNA polymerase II subunit + RNA polymerase II subunit B12.5 + RNA polymerase II subunit B32 + RNA polymerase II third largest subunit B44 + RNA polymerase subunit ABC10-alpha + RNA polymerase subunit ABC14.5 + RNA polymerase subunit ABC23 + RNA polymerase subunit ABC27 + Spt4/5 complex component + Transcription elongation factor 1 homolog	K. phaffii	115+118+ 1227+145+ 155+171+ 1743+186+ 214+304+ 72+83+85	ABCDEFGHIJKL MW:TN	ABCDEFGHIJKL MW:NT	X	14	1	2	3	Hetero 14-mer	4263	2089	2174
5ZX2	DNA-directed RNA polymerase subunit alpha + DNA-directed RNA polymerase subunit beta + DNA-directed RNA polymerase subunit beta' + DNA-directed RNA polymerase subunit omega + ECF RNA polymerase sigma factor SigH	M. tuberculosis	110+1174+ 1317+218+ 368	ABCDEF:GH	ABCDEF:GH	X	5	1	2	2.8	Hetero 6-mer	10331	5040	5291

^aPDB ID: Four letter protein data bank ID;
^bProtein: Name of the biomolecules; ^cSource Organisms: Source of the sequence obtained from various organisms;
^dProtein length: Length of the amino acid sequence; ^ePDB Chain Id: Chain Identifier from the PDB file;
^fBiological assembly: Functional unit of the molecules; ^gExperimental Methods: Biophysical methods used for the structure determination (X: X-ray, N:NMR);
^hProtein Entities: Number of proteins in a biological unit; ⁱRNA Entities: Number of RNAs in a biological unit;
^jDNA Entities: Number of DNAs in a biological unit; ^kOligomeric State: Total number of biomolecules in a biological assembly;
^lBSA: buried surface area.

Dataset Description